Gene information
Official symbol CLOCK
Official full name clock circadian regulator
Gene type protein-coding gene
Chromosome4q12
Alias symbolKIAA0334; KAT13D; bHLHe8
Gene familyBasic helix-loop-helix proteins; Lysine acetyltransferases
Resources
Entrez Gene 9575
HGNC HGNC:2082
Ensembl ENSG00000134852
Vega OTTHUMG00000102141
UCSC uc003hba.3
GO terms: 27 records
GO Description Category LogP Number of genes Detail
GO:0006974 cellular response to DNA damage stimulus GO Biological Processes -1.56334957 15 More
GO:0007623 circadian rhythm GO Biological Processes -8.17635164 13 More
GO:0010817 regulation of hormone levels GO Biological Processes -29.5190556 49 More
GO:0016570 histone modification GO Biological Processes -1.66018959 10 More
GO:0031347 regulation of defense response GO Biological Processes -64.5971043 148 More
GO:0031349 positive regulation of defense response GO Biological Processes -32.1301903 71 More
GO:0032103 positive regulation of response to external stimulus GO Biological Processes -58.7273809 118 More
GO:0032922 circadian regulation of gene expression GO Biological Processes -4.74914851 7 More
GO:0033143 regulation of intracellular steroid hormone receptor signaling pathway GO Biological Processes -4.62709399 7 More
GO:0033144 negative regulation of intracellular steroid hormone receptor signaling pathway GO Biological Processes -6.62830099 7 More
GO:0048511 rhythmic process GO Biological Processes -10.3377021 38 More
GO:0050708 regulation of protein secretion GO Biological Processes -30.3716714 63 More
GO:0050727 regulation of inflammatory response GO Biological Processes -68.5964592 121 More
GO:0050729 positive regulation of inflammatory response GO Biological Processes -38.1621935 57 More
GO:0051046 regulation of secretion GO Biological Processes -54.0079540 130 More
GO:0051090 regulation of DNA-binding transcription factor activity GO Biological Processes -25.8933515 78 More
GO:0051091 positive regulation of DNA-binding transcription factor activity GO Biological Processes -17.7436786 49 More
GO:0051223 regulation of protein transport GO Biological Processes -25.2801266 81 More
GO:0051775 response to redox state GO Biological Processes -3.36388958 3 More
GO:0060284 regulation of cell development GO Biological Processes -22.9455891 78 More
GO:0070201 regulation of establishment of protein localization GO Biological Processes -24.4831554 82 More
GO:0070888 E-box binding GO Molecular Functions -5.33490415 11 More
GO:0071214 cellular response to abiotic stimulus GO Biological Processes -11.2775864 23 More
GO:0071478 cellular response to radiation GO Biological Processes -4.2266687 10 More
GO:0071479 cellular response to ionizing radiation GO Biological Processes -1.9534599 4 More
GO:0104004 cellular response to environmental stimulus GO Biological Processes -11.2775864 23 More
GO:1903530 regulation of secretion by cell GO Biological Processes -45.6472055 114 More
Drug-Gene interaction
view
Related drugs: 2 records
Drug name Interaction type Source PMID View
albuterol PharmGKB 23508266 view
lithium PharmGKB 21047205 view
Related studies: 3 records
Molecular factor Omics type Application Objective MI type Reference
NM_004898.4:c.793-1130T>C genomics daytime sleepiness[other] myocardial infarction Skrlec I et al. Adv Med Sci. 2019
NC_000004.12:g.55502504G>A genomics myocardial infarction[diagnosis] myocardial infarction Skrlec I et al. J Clin Med. 2020
NM_004898.4:c.1450-143A>G genomics myocardial infarction[diagnosis] myocardial infarction Skrlec I et al. J Clin Med. 2020
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